ChloroquineV1, France, Analysis, bibRecord, 000185

Adherence to treatment in systemic lupus erythematosus patients

Identifieur interne : 000185 ( France/Analysis ); précédent : 000184; suivant : 000186

Adherence to treatment in systemic lupus erythematosus patients

Auteurs : Nathalie Costedoat-Chalumeau [France] ; Jacques Pouchot [France] ; Gaëlle Guettrot-Imbert [France] ; Veronique Le Guern [France] ; Gaëlle Leroux [France] ; Donata Marra [France] ; Nathalie Morel [France] ; Jean-Charles Piette [France]

Source :

Best Practice and Research: Clinical Rheumatology [ 1521-6942 ] ; 2013-06.

RBID : Hal:hal-01791229

English descriptors

mix :
- Adherence, Compliance, Flare, Hydroxychloroquine, Systemic lupus erythematosus, Therapeutic drug monitoring.

Abstract

Adherence is defined as "the extent to which a person's behaviour coincides with medical or health advice." Poor adherence to therapeutic regimens is a common and expensive problem in patients with chronic diseases including systemic lupus erythematosus (SLE) and is associated with a higher risk of flares, morbidity, hospitalisations and poor renal outcome. Non-adherence to the treatment is multifactorial for most patients and varies according to unintentional or intentional patterns. The rates of non-adherence in SLE patients range from 3% to 76% depending on the assessment methods, which are all subject to limitations. Indeed, poor adherence to therapeutic regimens is difficult to evaluate. Two studies have shown that undetectable blood hydroxychloroquine (HCQ) concentration may be a simple, objective and reliable marker of non-adherence in SLE patients. The accurate diagnosis of non-adherence may prevent one from incorrectly interpreting disease manifestations as a lack of response. It may then avoid an unnecessary or even dangerous treatment escalation.

Url:

https://hal.univ-lorraine.fr/hal-01791229

DOI: 10.1016/j.berh.2013.07.001

Affiliations:

France

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: 000013
to stream Hal, to step Curation: 000013
to stream Hal, to step Checkpoint: 000133
to stream Main, to step Merge: 001096
to stream Main, to step Curation: 001095
to stream Main, to step Exploration: 001095
to stream France, to step Extraction: 000185

Links to Exploration step

Hal:hal-01791229

Le document en format XML

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</analytic>
<idno type="DOI">10.1016/j.berh.2013.07.001</idno>
<series><title level="j">Best Practice and Research: Clinical Rheumatology</title>
<idno type="ISSN">1521-6942</idno>
<imprint><date type="datePub">2013-06</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term>Adherence</term>
<term>Compliance</term>
<term>Flare</term>
<term>Hydroxychloroquine</term>
<term>Systemic lupus erythematosus</term>
<term>Therapeutic drug monitoring</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">              <p>Adherence is defined as "the extent to which a person's behaviour coincides with medical or health advice." Poor adherence to therapeutic regimens is a common and expensive problem in patients with chronic diseases including systemic lupus erythematosus (SLE) and is associated with a higher risk of flares, morbidity, hospitalisations and poor renal outcome. Non-adherence to the treatment is multifactorial for most patients and varies according to unintentional or intentional patterns. The rates of non-adherence in SLE patients range from 3% to 76% depending on the assessment methods, which are all subject to limitations. Indeed, poor adherence to therapeutic regimens is difficult to evaluate. Two studies have shown that undetectable blood hydroxychloroquine (HCQ) concentration may be a simple, objective and reliable marker of non-adherence in SLE patients. The accurate diagnosis of non-adherence may prevent one from incorrectly interpreting disease manifestations as a lack of response. It may then avoid an unnecessary or even dangerous treatment escalation.</p>
            </div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
</list>
<tree><country name="France"><noRegion><name sortKey="Costedoat Chalumeau, Nathalie" sort="Costedoat Chalumeau, Nathalie" uniqKey="Costedoat Chalumeau N" first="Nathalie" last="Costedoat-Chalumeau">Nathalie Costedoat-Chalumeau</name>
</noRegion>
<name sortKey="Guettrot Imbert, Gaelle" sort="Guettrot Imbert, Gaelle" uniqKey="Guettrot Imbert G" first="Gaëlle" last="Guettrot-Imbert">Gaëlle Guettrot-Imbert</name>
<name sortKey="Le Guern, Veronique" sort="Le Guern, Veronique" uniqKey="Le Guern V" first="Veronique" last="Le Guern">Veronique Le Guern</name>
<name sortKey="Leroux, Gaelle" sort="Leroux, Gaelle" uniqKey="Leroux G" first="Gaëlle" last="Leroux">Gaëlle Leroux</name>
<name sortKey="Marra, Donata" sort="Marra, Donata" uniqKey="Marra D" first="Donata" last="Marra">Donata Marra</name>
<name sortKey="Morel, Nathalie" sort="Morel, Nathalie" uniqKey="Morel N" first="Nathalie" last="Morel">Nathalie Morel</name>
<name sortKey="Piette, Jean Charles" sort="Piette, Jean Charles" uniqKey="Piette J" first="Jean-Charles" last="Piette">Jean-Charles Piette</name>
<name sortKey="Pouchot, Jacques" sort="Pouchot, Jacques" uniqKey="Pouchot J" first="Jacques" last="Pouchot">Jacques Pouchot</name>
</country>
</tree>
</affiliations>
</record>

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Adherence to treatment in systemic lupus erythematosus patients

Adherence to treatment in systemic lupus erythematosus patients

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